In 1-fluoropentane does the fluoride form hydrogen bonds to hydrogens on the carbon 5 methyl group?

David F asked:

Will the Newman projection surrounding carbon 2 - carbon 3 (substituents being ethyl group and C˒F) be gouche?

One Response to “In 1-fluoropentane does the fluoride form hydrogen bonds to hydrogens on the carbon 5 methyl group?”

  1. No, the hydrogens bonded to carbon will essentially never form hydrogen bonds.

    The favored configuration will be “anti” rather than “gauche.”

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